Progesterone Injection – Progesterone is a hormone required for uterine lining growth and maintenance and during intercourse. It aids in the regulation of the menstrual cycle, the generation of milk, and sexual function. Menopause, uterine fibroids, endometriosis, and ovarian cancer are all treated with progesterone injections. It is also used to avoid conception following an abortion or miscarriage. If you want to take progesterone injections, be sure you understand what they are used for, the benefits, side effects, dose, and price.

Progesterone Injection

Progesterone is a naturally existing hormone that controls menstruation and ovulation. The ovaries create a large quantity of progesterone in women. It is also generated in lower levels by both men’s and women’s adrenal glands. Progesterone I s used to induce menstruation in the female who has not yet achieved Menopause but aren’t getting periods owing to a progesterone deficiency in their bodies. It is also utilized to reduce uterine lining enlargement in postmenopausal women getting estrogen hormone replacement treatment.

Menopause, premenstrual syndrome (PMS), and advanced breast cancer are among illnesses that can be treated with progesterone injection. It works by regulating hormone levels in the body, which aids in the restoration of balance and the reduction of symptoms. 

Progesterone Injection Uses

The following are the most common uses for progesterone injections:

  • 1. PMS: Progesterone injectable treatment is frequently administered to women before the start of their period to ease symptoms such as cramping, bloating, mood changes, and lethargy.
  • 2. Perimenopause: A natural decline in estrogen levels causes many women to endure a variety of unpleasant symptoms like vaginal dryness and osteoporosis during perimenopause. Progesterone injection treatment may help alleviate these symptoms by restoring estrogen levels to normal.
  • 3. Postpartum depression is a disorder that affects one out of every five new moms after giving birth. It can linger for up to six months after the baby is delivered, causing substantial emotional issues for both the mother and the infant. Progesterone injection treatment may enhance the mother’s mood and psychological well-being by raising estrogen levels in the body.

Benefits of Progesterone Injection

Progesterone injection is a hormone treatment used to treat various conditions such as premenstrual syndrome (PMS), endometriosis, and fibroids. It is also used to induce ovulation in women unable to conceive or having problems getting an abortion. Progesterone injectable treatment has various benefits, including the following:

  • 1. Relieves PMS symptoms such as cramping, bloating, and mood changes.
  • 2. Reduce the discomfort and inflammation caused by endometriosis.
  • 3. Alleviates Menopause.
  • 4. Enhance fertility by boosting ovulation and allowing more embryos to implant on the uterine wall.
  • 5. Anxiety and depression relief
  • 6. Boosts energy levels
  • 7. Improve menstrual flow and reduce the severity of fibroids.

Causes of Progesterone Injection

Some of the causes that require progesterone injection are as follows:

  • 1. Prevention of early labor.
  • 2. Treat conditions like endometriosis, fibroids, premenstrual syndrome (PMS), and breast cancer.
  • 3. Lower estrogen levels in the body
  • 4. Used as a form of contraception
  • 5. Used as part of a long-term contraceptive strategy.
  • 6. Boost fertility in females who are trying to get pregnant.

Side Effects of Progesterone Injection

Because progesterone injections are frequently administered to women experiencing symptoms such as heavy periods, PMS, and infertility, it’s vital to be informed of the potential adverse effects. Progesterone injection side effects may include:

  • 1. Nausea and vomiting
  • 2. Breast tenderness
  • 3. Mood swings
  • 4. Hot flashes
  • 5. Irregular menstrual periods
  • 6. Fatigue
  • 7. Acne
  • 8. Swelling and pain in the injection area
  • 9. Headache
  • 10. Increase in facial hair
  • 11. Weight gain or loss
  • 12. Scalp hair loss
  • 13. Dizziness or drowsiness
  • 14. Dry skin

Progesterone Injection Price in India

The cost of progesterone injections varies depending on where you reside, but they are typically reasonably priced. Progesterone injections are priced between each injection. The dose is often determined by the ailment being treated. The MRP for Progesterone solution 2 ml is around Rs. 109.50. The typical price varies based on the vendor and pharmacy and ranges between Rs. 95 and Rs. 100.

How does progesterone injection work?

Progesterone injection is a hormone treatment used to treat various illnesses such as Menopause and postpartum women’s syndrome. It works by raising progesterone levels in the body, which helps to alleviate symptoms, including vaginal dryness, cramps, mood swings, and anxiety. Various varieties of progesterone injections are on the market, each with its advantages and disadvantages. The most popular is the intramuscular injection, which is typically administered every four weeks. However, transdermal (on the skin) formulations are also available.

Progesterone Injection Composition

Progesterone injections include progesterone composition. It is the primary chemical responsible for improving numerous elements of women’s health in the body. It aids in the relief of symptoms such as mood swings, hot flashes, vaginal dryness, and weariness. It can also help lower uterine inflammation, discomfort, and stress hormone levels.

Dosage of Progesterone Injection

Progesterone injection dose varies according to the individual’s health and weight. To treat amenorrhea, take 5 to 10 milligrams every 6 to 8 hours continuously for eight days. Five to ten milligrams daily for six doses are recommended for functional uterine bleeding. If menstruation occurs during the course, the shots should be stopped.


Warnings to use the progesterone injection are as follows:

  • 1. Do not combine estrogen with a progesterone injection to avoid heart disease. Combining estrogen and progestin may increase the risk of suffering a heart attack, breast cancer, stroke, a blood clot, etc.
  • 2. If you are allergic to progesterone or another component of the progesterone injection.
  • 3. If you are experiencing unexpected vaginal bleeding.
  • 4. If you have recently suffered from a miscarriage.

When to use progesterone injection?

  • 1. You have symptoms such as irregular periods, breast pain, or infertility.
  • 2. When attempting to conceive, your menstrual cycle does not follow the normal pattern.
  • 3. To increase the consistency of your menstrual cycle.
  • 4. Endometriosis treatment
  • 5. PMS symptoms such as mood swings, anxiety, and exhaustion can be treated with this medication.
  • 6. You should also take progesterone injections if you have difficulties getting pregnant, such as a low sperm count or difficulty maintaining a pregnancy.

When not to use progesterone injection?

  • 1. Before receiving a progesterone injection, tell your doctor if you are suffering pain.
  • 2. Progesterone injections should be avoided if you are nursing since they might alter breast milk production.
  • 3. Before taking progesterone injection, you should visit your doctor if you have any other medical condition.
  • 4. If you use birth control tablets.
  • 5. If you are pregnant and already have a uterine infection.


Finally, progesterone injection is an excellent alternative for folks who desire to get pregnant quickly. It can help with Menopause and reproductive concerns. You can also utilize progesterone if your cycles have grown more regular and heavier due to an aging uterus. Though doctors only recommend Progesterone Injection when previous infertility treatments have failed, it is always best to speak with a fertility professional before administering this injection. This can be done if you have irregular periods, low testosterone levels, or irregular ovulation cycles.

Frequently Asked Questions

Why is progesterone injection given during pregnancy?

The progesterone injection can aid in the prevention of premature birth. It is given to pregnant ladies to reduce the chance of premature delivery. It contains the progesterone hormone, which aids in the prevention of contractions.

What happens after taking a progesterone injection?

After receiving a progesterone injection, you may have pain/swelling at the injection site, headache, breast tenderness, weight loss/gain, acne, increased body or facial hair, nausea, loss of scalp hair, dizziness, or sleepiness. Inform your doctor right away if such symptoms persist or worsen.

When is progesterone injection given?

Doctors advise starting progesterone injections in the second trimester and repeating them till 36 weeks. Doctors start giving the injections around 16 and 24 weeks of pregnancy.

Can progesterone injection stop miscarriage?

Progesterone is a hormone that is required to keep a pregnancy going. It may lower the chance of miscarriage in women who have early pregnancy bleeding.

What is the benefit of progesterone injection?

Progesterone Injection is a medication prescribed to treat irregular menstrual bleeding caused by low hormone levels.

Is progesterone injection useful for conceiving?

Progesterone can be administered intramuscularly or vaginally. There is no distinction in the probability of becoming conceived or sustaining a pregnancy whether progesterone is administered intravenously.

What should I do after receiving a progesterone injection?

After injecting yourself, relax the injection site with a heating pad. Since progesterone is present in the oil, it may take some time to enter the muscles.

How long does it require for a progesterone injection to take effect?

If she began at a different point in her cycle, she would need to take backup birth control or refrain from having intercourse for the initial 7 days following receiving the injection.

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