Almost all types of anal fissures recover on their own and do not require any treatment. If the tears do not mend on their own, we must resort to other therapies. This might comprise prescription medications, creams and ointments, and others. This article contains all the information you need about anal fissure ointment.

What is anal fissure ointment?

Anal fissure ointment is a topically administered medication that helps enhance blood circulation to the fissure, accelerate healing, and loosen the anal sphincter. These medications are prescribed to relieve symptoms of severe discomfort caused by persistent anal fissures. Fissure ointment is often considered the best therapeutic option when other conservative treatments fail.

Nitroglycerin Ointment for Fissure Treatment

Nitroglycerin is the best ointment for fissure treatment used to treat severe anal fissures. It is a kind of medication known as nitrate. It works by relaxing the muscles surrounding the anus, reducing discomfort and stress in the anus area. This substance comes in ointment dose forms. This medication is only accessible with a medical recommendation.

Avoid overdosing and use it more frequently. Also, prevents its usage for a prolonged period than your doctor has prescribed. The fissure ointment is solely for rectal usage. It should not go into your eyes, mouth, nose, or vagina. If it does go into these places, promptly wash it out.


To use the anal fissure ointment, follow the below tips:

  • 1. Before applying the medication, clean your hands.
  • 2. Use a finger cot or a disposable medical glove to cover your hands.
  • 3. Place the covered finger near the dose line on the prescription box’s side, and your fingertip must be at one side of the dosage line.
  • 4. Squeeze a little amount of fissure ointment on your fingertips. The quantity of the ointment must be similar to the length of the dosage line.
  • 5. Softly place your fingertips with the medicines into the anal canal. Do not extend your finger beyond the first joint.
  • 6. Administer the ointment to the interior lining of the anal canal with care.
  • 7. If the anal canal is excessively painful, spread the ointment straight to the outer skin.
  • 8. Throw away the finger coverings and clean your hands.


This medication’s dosage will vary depending on the patient, following your doctor’s instructions or the label’s instructions. This information only reflects the typical dosages of this medication. If your dose differs, do not increase it until your doctor instructs you to use it. 

The potency of the medication determines the dosage of medicine you ingest. In addition, the number of dosages you apply every day, the duration between dosages, and the duration you take medications are all determined by the health illness for which you are consuming the medication. For administration of anal fissure ointment:

  • 1. Adult: Apply 1 inch into the anus after twelve hours.
  • 2. Children: Usage and dosage must be approved by a doctor.


  • 1. Keep this best ointment for fissures out of children’s range.
  • 2. Do not retain expired or no longer useful medications.
  • 3. Inquire with your healthcare provider about properly disposing of any medications you do not require anymore.
  • 4. Keep the medication at ambient temperature in a well-sealed container. Prevent it from moisture, heat, direct light, and freezing.
  • 5. After using the medication, maintain the tube securely closed. Discard any leftover medicine eight weeks after starting using the tube.

Anal Fissure Medications

A doctor may prescribe various medications to alleviate your discomfort and enable the anal fissure to cure. Usually, anal fissures can be healed with fissure ointment, pain reliever creams, or over-the-counter laxatives. To avoid muscular spasms that aggravate the problem, fissures that do not cure will necessitate drugs that soften the anal sphincter. These drugs are generally enough to let the tissues repair on their own.

  • A. Laxatives

Laxatives are medications that aid you to poop effortlessly. Individuals experiencing an anal fissure are typically given bulk-forming laxative pills or granules. These functions by retaining liquid in your feces, making it softer and less prone to dry out.

An osmotic laxative oral treatment is commonly administered for youngsters with an anal fissure. This laxative promotes the body’s desire to excrete by raising the amount of liquid in the colon. A doctor may advise commencing with a modest dose and increasing steadily in a few days unless you can release soft stool.

  • B. Topical Anesthetics

If you experience significant anal discomfort, your doctor may recommend a topical anesthetic to sedate the anus when you defecate. A topical medication is directly applied to the troubled region. It would not cure fissures. However, it relieves discomfort. Lidocaine cream, for example, blocks the nerves that convey pain. They are available over the counter and can be administered directly to the affected area to offer momentary relief. When addressing persistent anal fissures, a doctor will frequently recommend lidocaine cream.

  • C. Nitroglycerin                  

The first-line treatment of severe anal fissures is the topical application of Nitroglycerin, which relaxes the anal muscles. Nitroglycerin, the best ointment for fissures, is often used to calm blood vessels. It is the most effective drug for easing the anal sphincter and curing fissures. A compounding pharmacy is required to prepare nitroglycerin ointment.

  • D. Calcium-channel blockers

Calcium channel blockers, like diltiazem, are a kind of medication that is commonly prescribed for hypertension. Calcium channel blockers ease the sphincter muscle and increase blood flow to the fissures. Furthermore, the calcium channel blockers administered straight to the anus effectively treat certain persons with anal fissures. 

These medications are believed to be roughly as helpful as GTN (Glyceryl Trinitrate Ointment) in healing anal fissures and are prescribed if other medications have not been beneficial.

When you’re using the medication, you may get dizziness, headaches, itching, or blistering in the area. Any negative impacts should subside within a few days as the body adapts to the medication.

  • E. Botulinum toxin injection

After conservative medication therapy fails, botulin toxin A, more frequently referred to as Botox, is extremely successful in softening the anal sphincter. When injected underneath the tissues surrounding the anal sphincter, Botulinum toxin relieves the anal sphincter and diminishes or avoids spasms for two to three months following the injection.

Botulinum toxin, such as nifedipine and diltiazem, has not been authorized by the FDA for treatment. Several individuals will be pain-free within a few weeks. However, there are no accurate data on its success since there is no guideline or norm. On the other hand, Botulinum toxin injections are prohibitively costly, not covered by health insurance, and excruciatingly unpleasant.

Is Vaseline Good for Fissures?

Vaseline is a wound dressing. When applied to a tiny cut, it soothes the skin by shielding the area from additional harm or infection and creating a moist environment for healing. An anal fissure resembles a cut. However, it is produced by tissue separation. Though Vaseline might help with symptoms, the purpose of anal fissure therapy is to prevent the break from tearing apart. Loosening the stools or easing the anal sphincter helps in preventing the breaks. Vaseline might assist in calming the affected area around the anus.

What is the best cream for fissures?

Your doctor may suggest you use the best cream to cure anal fissures:

  • 1. Nitroglycerin (Rectiv) can be administered topically to enhance blood circulation to the anal fissure. It facilitates healing and softens the anal sphincter.
  • 2. Pain alleviation could be aided by topical anesthetic creams like lidocaine hydrochloride (Xylocaine).

Smuth Ointment for Anal Fissure

Smuth Ointment for anal fissures is a medication used to treat or prevent severe issues like piles and anal fissures. It improves the pain, stiffness, irritation, and feces emptying problems in those with anal issues. Smuth Cream 30 gm may give relief from anal fissure discomfort. Lignocaine is a local anesthetic that reduces pain and is included in Smuth Cream 30 gm.

This anal fissure ointment relieves pain, increases blood flow, lowers leakage and vein collapse, and inhibits blood clotting. This efficiently improves piles-related discomfort, edoema, irritation, and itching. Moreover, it possesses antioxidant qualities that help fissures recover. To get the most out of Smuth Cream, apply it exactly as directed. Avoid hot, oil-rich foods and consume enough fiber to help digestion and assure a fast recovery.

Best Medicines for Anal Fissure

The optimum anal fissure medicine will be associated with the seriousness of the problem and the person’s sensitivity to adverse effects. Fiber supplements and a topical anesthetic are generally adequate to speed up the recovery process for severe anal fissures.

The purpose of management of acute anal fissures is to soften the anal sphincter to heal the break. Nitroglycerin, an effective fissure ointment, also produces terrible headaches. Thus sufferers may have to depend on less effective medicine. The best part is that several anal fissure medication regimens are quite successful. Some of the effective medications are mentioned as under:

  • 1. Nitroglycerin Cream
  • 2. Lidocaine Cream
  • 3. Botox A Injection
  • 4. Diltiazem
  • 5. Nifedipine

Top 4 Painkillers Tablet for Anal Fissure

The most troubling indication of an anal fissure is discomfort, especially while passing feces. Simple painkillers may be effective in alleviating anal fissure discomfort. Among the most efficient anal fissure pain reliever medications are:

  • 1. Paracetamol
  • 2. Ibuprofen
  • 3. Diltiazem
  • 4. Nifedipine

These four painkiller tablets can be taken orally or administered topically and are used if Nitroglycerin is ineffective or produces considerable negative effects. It is suggested to avoid using soap on the anal area after using the toilet since this may aggravate the painful skin. Furthermore, the discomfort of passing feces can be substantially reduced by periodically immersing the area in a warm sitz bath to relax the muscles of the anal sphincters.


Anal fissures cause a lot of tension and discomfort. Some may cure themselves, but some needs severe treatments. Along with oral medications, anal fissure ointment is the best treatment. Also, you can consider consuming the painkillers mentioned above if you suffer severe pain and discomfort due to an anal fissure.

Frequently Asked Questions

Which ointment is best for fissures?

Nitroglycerin is the most effective anal fissure ointment for treating acute anal fissures. It reduces tension and suffering in the anus region by promoting relaxation around the anus muscles. It includes nitrate, which is a type of drug.

What is the fastest way to heal a fissure?

Anal fissures usually get better within 2 to 4 weeks when appropriate precautions are taken to ease stool passing. Such precautions include boosting your fiber and hydration intake. Trying a sitz bath for 10 to 20 minutes many times a day, particularly after bowel motions, can aid sphincter relaxation and recovery.

Can ointment heal fissures?

Fissure ointment does not completely heal the fissures. However, it may assist individuals in coping with the pain and stress caused by fissures.

Which antibiotic is best for fissures?

Topical antibiotic therapy with metronidazole alongside traditional medical therapies for the severe anal fissure is an efficient and safe method that eliminates pain and healing faster.

How do I know if I have hemorrhoid or fissure?

The primary distinction between anal fissures and hemorrhoids is that anal fissures often manifest primarily after bodily functions, but hemorrhoids are unpleasant during the day. However, without a physical assessment, this disparity in indications is frequently highly informative about the patient’s condition.

Can fissures get infected?

An anal fissure could become infectious and grow into an infection. However, this is quite uncommon. Until surgery is undertaken, treating anal fissures with antimicrobial medicines and topical antibiotics is not considered standard treatment.

Does coconut oil heal fissures?

The anoderm, where several anal fissures arise, lacks sweat glands, hair follicles, and oil glands. Hence it is relatively dry. Since anoderm resembles dry skin, moisturizers like coconut oil are frequently recommended for anal disorders such as hemorrhoids or fissures. By minimizing further stress and relaxing the anal sphincter, a moisturizer may make the anal area more pleasant and allow the fissure to cure.

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