Dolo 650 Tablet works by blocking the release of certain chemical messengers that are involved in pain and fever and thus helps in relieving pain and fever. It is used in the treatment of headache, migraine, neuralgia, toothache, sore throat, period pain, arthritis, muscle pain and cold.

Dolo 650 Tablet has been the most popular of the paracetamol based drugs prescribed by doctors during the COVID-19 pandemic. It should be taken regularly as per doctor’s advice. Take it with food to avoid stomach upset. It can be taken alone or in combination with other medicines. However, no more than four doses of Dolo 650 Tablet should be taken in 24 hours with a gap of at least 4 hours between two doses. Please do not take it for longer than the duration prescribed by the doctor.

Dolo 650 Tablet is generally tolerated easily and the side effects are very few. However, in some people it may cause temporary abdominal pain, nausea and vomiting. If any of these side effects persist or are bothering you, consult a doctor.

Though Dolo 650 Tablet is safe but it may not be useful for everyone. If you have any liver or kidney problems, you are allergic to it or you are taking any other medicines, tell your doctor about all these before taking this medicine as these things can affect the dosage and effect of the medicine can. In general, try to take the lowest dose that is effective in relieving the pain at that time. Most of the women take it during pregnancy or breastfeeding as painkillers.



fever treatment

Dolo-650 can cause these side effects

Common side effects of Dolo 650


2. Low blood pressure

3. Dizziness

4. Feeling weak

5. Excessive sleepiness

6. Feeling unwell

7. Constipation

8. Feeling faint

9. Dry mouth

10. UTI

Serious side effects 0f Dolo 650

 1. Slow heart beat

2. Swelling of vocal cord

3. Lung infection

4. Shortness of breath

5. Nervous system affected

6. Increased heartbeat

Interaction between Food and Dolo 650 Tablet

Due to lack of research, complete information is available on the side effects of taking Dolo 650 Tablet with food on the body.

What are the side effects of consuming alcohol while taking Dolo 650 Tablet?

Alcohol and Dolo 650 Tablet can have many serious effects on your body. To avoid this, you have to consult a doctor



It is not safe to drink alcohol while taking Dolo 650 Tablet.


Use of the Dolo 650 Tablet during pregnancy may be dangerous. Despite the paucity of research in humans, animal studies indicate that it might have negative effects on a baby’s development. Your doctor will weigh the potential advantages against the risks before recommending usage. Please speak with your physician.


Use of the Dolo 650 Tablet while Breastfeeding is safe. Studies have revealed that this medication is safe for the baby and does not significantly enter the breastmilk.


Usually, Dolo 650 Tablet has no effect on your ability to drive.


Patients with kidney disease should use the Dolo 650 Tablet with extreme caution. Dolo 650 Tablet dosage may need to be changed. Please speak with your physician. The safest painkiller for kidney diseases is paracetamol, which is present in Dolo 650 Tablet.


Patients with liver disease should use the Dolo 650 Tablet with caution. Dolo 650 Tablet dosage may need to be changed. Please speak with your physician. However, patients with severe liver disease and active liver disease are not advised to take Dolo 650 Tablet.

Special tips

1. To prevent stomach upset, take the Dolo 650 Tablet with food or milk.

2. Take it for the amount of time and in the dosage that the doctor has advised. Serious side effects, such as stomach bleeding and kidney issues, may result from prolonged use.

3. Dolo 650 Tablet should not be taken within two hours of antacids, which are digestive aids.

4. Avoid drinking alcohol while taking this medication because it may increase your risk of experiencing stomach issues.

5. Be sure to let your doctor know if you have liver issues so that the medication’s dosage can be adjusted.

6. Your doctor may routinely check the function of your kidneys, liver, and levels of various blood components if you are taking this medication for a prolonged period of time.

Alternative Brands of Dolo 650 Tablet

This information is for informational purposes only. Please consult doctor before taking any medicine.

Dolo 650 Tablet


PUC 650 Tablet

Alkem Laboratories Ltd.


Wellset 650 Tablet

Sun Pharmaceutical Industries Ltd.


XTPara 650mg Tablet

Torrent Pharmaceuticals Limited


Rupar 650 mg Tablet

Medispan Limited


Pacimol 650 Tablet

IPCA Laboratories Limited


Facts about Dolo 650 Tablet

chemical class

P-Aminophenol Derivative

prone to addiction


therapeutic class


action class

Analgesic & Antipyretic-PCM

Frequently Asked Question on Dolo 65 Tablet

What to do if you are allergic to Dolo?

Do not use if you are allergic to Dolo. Ask your doctor about alternatives to Dolo.

What are the precautions to be taken while taking Dolo?

Dolo is completely safe to consume and does not require much caution. However, do not drink alcohol at all. If you have a history of kidney or liver disease, please consult your doctor before taking Dolo.

Can I take Dolo with antihistamine medicine?

Yes, it is safe to take Dolo with antihistamine drugs that have a milder sedative effect, such as cetirizine and loratadine. No harmful effects have been reported so far. However, other groups of anti-histamine drugs such as chlorpheniramine, diphenhydramine, etc. can cause dizziness or excessive sleepiness. These two medicines should not be taken at the same time without doctor’s advice.

Can I take Dolo with aspirin?

Yes, Dolo can be taken with aspirin. No side effects have been reported so far by taking these two medicines together. But you must consult a doctor before taking these two medicines together.

How does Dolo work?

It is believed that Dolo acts on the central nervous system (brain and spine). Dolo prevents the release of prostaglandins (a natural compound that acts like a hormone) responsible for increasing body temperature and pain. Due to the effect of this medicine, the brain stops receiving pain messages.

How many times a day can I take Dolo 650?

One or two Dolo 650 tablets may be taken every four hours and the total dose should not exceed 4000 mg. Therefore, it is safe to take 5 to 6 tablets in a day .

Q. Is Dolo 650 Tablet an antibiotic?

No, Dolo 650 Tablet is not an antibiotic. It works as a pain reliever and fever reducer.

Q. How long does it take for Dolo 650 Tablet to work?

It takes about 30-45 minutes for Dolo 650 Tablet to start working and show its effect. It is advisable to take this medicine for the duration recommended by the doctor. If you are suffering from any side effects, consult a doctor.


Glamyo Health objective is to ensure that its consumers get expertly tested, accurate and reliable information. The information provided here should not be taken as a substitute for medical advice. The details given here are for your information only. It may not include all the information about a specific health problem, lab tests, medicines and all their possible side effects, interactions, and their associated precautions and warnings. For all your questions related to any medicine or disease, contact the doctor. Our aim is to strengthen the relationship between doctor and patient, not to be his substitute.

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